2-(2-溴苯氧基)四氢-2H-吡喃合成路线 （共 2 条）
反应条件
pyridinium p-toluenesulfonate in dichloromethane
T=20°C; 16 h;
参考文献
Symyx Technologies, Inc.
Patent: US2004/14950 A1, 2004 ;
Location in patent: Page 41 ;
反应条件
1.1: Mg; I2 / tetrahydrofuran / 0.5 h / 60 °C
1.2: tetrahydrofuran; diethyl ether / 1.5 h / -78 °C
1.3: 68 percent / PPTS / ethanol / 1 h / Heating
2.1: Huenig's base / diethyl ether / 2 h / 20 °C
2.2: 68 percent / formic acid / 21 h / 20 - 60 °C
3.1: 100 percent / TFA / toluene / Heating
View Scheme
参考文献
Saaby, Steen; Nakama, Kimitaka; Lie, Mette Alstrup; Hazell, Rita G.; Jorgensen, Karl Anker
Chemistry - A European Journal, 2003 , vol. 9, # 24 p. 6145 - 6154
