反应条件
1: 78 percent / LDA / tetrahydrofuran / 1 h / Ambient temperature 2: 1) Na, liq. NH3, 2) H3O(1+) 3: 24 percent / PhOPOCl2, DMF / CH2Cl2 / Ambient temperature 4: 89 percent / HCl gas / diethyl ether / 0 °C 5: 55 percent / NaCNBH3 / tetrahydrofuran; H2O / 3 h / Ambient temperature; pH = 4 6: 1) DBU, 2) NaN3 / 1) CH2Cl2, 0 deg C, 2) acetone, H2O, RT 7: 1) H2O, 2) 48percent HBr / 1) 150 deg C, 2 h in autoclave, 2) reflux, 2 h View Scheme
参考文献
Tetrahedron Letters, , vol. 35, # 16 p. 2615 - 2618
