6-甲氧基-4-二氢色原酮合成路线 （共 23 条）
反应条件
1: 65 percent / concentrated hydrochloric acid / 6 h / Heating 2: thionyl chloride / toluene / 1.5 h / Heating 3: trifluoromethanesulfonic acid / CHCl3 / -65 - 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 33, # 1 p. 445 - 450
反应条件
1: butyl lithium, p-toluene sulfonyl chloride / diethyl ether 2: 75 percent / ethylene glycol / 4 h / 180 °C View Scheme
参考文献
Tetrahedron, , vol. 45, # 1 p. 309 - 318
反应条件
air in various solvent(s) 8 h; Heating; Yield given;
参考文献
Tetrahedron Letters, , vol. 27, # 18 p. 2041 - 2042
反应条件
1: hydroxylamine hydrochloride, potassium carbonate / ethanol 2: hydrogene / Raney nickel / ethanol View Scheme
参考文献
Pratap, Ram; Gupta, R. C.; Anand, Nitya
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1981 , vol. 20, # 12 p. 1063 - 1067
反应条件
hydrogenchloride in ethanol 24 h; Ambient temperature;
参考文献
Nakib, Tahsin Al; Tyndall, D. Vivian; Meegan, Mary Jane
Journal of Chemical Research, Miniprint, 1987 , # 10 p. 2743 - 2772
反应条件
hydrogenchloride in ethanol 24 h; Ambient temperature;
参考文献
Nakib, Tahsin Al; Tyndall, D. Vivian; Meegan, Mary Jane
Journal of Chemical Research, Miniprint, 1987 , # 10 p. 2743 - 2772
反应条件
hydrogenchloride in ethanol 24 h; Ambient temperature;
参考文献
Nakib, Tahsin Al; Tyndall, D. Vivian; Meegan, Mary Jane
Journal of Chemical Research, Miniprint, 1987 , # 10 p. 2743 - 2772
反应条件
hydrogenchloride in ethanol 24 h; Ambient temperature;
参考文献
Al Nakib; Bezjak; Meegan; Chandy
European Journal of Medicinal Chemistry, 1990 , vol. 25, # 5 p. 455 - 462
反应条件
sodium azide; sulfuric acid
参考文献
Deng, Xian-Qing; Song, Ming-Xia; Wei, Cheng-Xi; Sun, Zhi-Gang; Quan, Zhe-Shan
Medicinal Chemistry Research, 2011 , vol. 20, # 7 p. 996 - 1004
反应条件
bromine in diethyl ether; dichloromethane
参考文献
Pfizer Inc,
Patent: US6166031 A1, 2000 ;
