3-氯-6-(4-甲氧苯基)哒嗪合成路线 （共 11 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); caesium carbonate in 1,4-dioxane Suzuki Coupling; HeatingInert atmosphere; chemoselective reaction;
参考文献
Urgin, Karene; Aube, Christophe; Pipelier, Muriel; Blot, Virginie; Thobie-Gautier, Christine; Sengmany, Stephane; Lebreton, Jacques; Leonel, Eric; Dubreuil, Didier; Condon, Sylvie
European Journal of Organic Chemistry, 2013 , # 1 p. 117 - 124
反应条件
trichlorophosphate T=0°C; 6 h; Heating / reflux;
参考文献
BANYU PHARMACEUTICAL CO., LTD.
Patent: EP1719756 A1, 2006 ;
Location in patent: Page/Page column 43 ;
EP 1719756 A1
反应条件
palladium diacetate; triphenylphosphine; cesium fluoride in N,N-dimethyl-formamide T=90°C; Inert atmosphere; chemoselective reaction;
参考文献
European Journal of Organic Chemistry, , # 1 p. 117 - 124
反应条件
tetrakis(triphenylphosphine) palladium(0); caesium carbonate in 1,4-dioxane Suzuki Coupling; HeatingInert atmosphere; chemoselective reaction;
参考文献
European Journal of Organic Chemistry, , # 1 p. 117 - 124
反应条件
palladium diacetate; triphenylphosphine; cesium fluoride in N,N-dimethyl-formamide T=90°C; Inert atmosphere; Reagent/catalyst; chemoselective reaction;
参考文献
European Journal of Organic Chemistry, , # 1 p. 117 - 124
反应条件
palladium diacetate; triphenylphosphine in N,N-dimethyl-formamide T=90°C; 4 h; Inert atmosphere; Catalytic behavior; Reagent/catalyst; chemoselective reaction;
参考文献
Urgin, Karene; Aube, Christophe; Pipelier, Muriel; Blot, Virginie; Thobie-Gautier, Christine; Sengmany, Stephane; Lebreton, Jacques; Leonel, Eric; Dubreuil, Didier; Condon, Sylvie
European Journal of Organic Chemistry, 2013 , # 1 p. 117 - 124
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=20°C; 24 h;
参考文献
Tetrahedron Letters, , vol. 46, # 8 p. 1303 - 1305
反应条件
1: hydrazine hydrate / butan-1-ol / 6 h / 100 °C 2: H2 / Raney Ni / methanol / 20 °C / 760 Torr View Scheme
参考文献
Wermuth, Camille-Georges; Bourguignon, Jean-Jacques; Schlewer, Gilbert; Gies, Jean-Pierre; Schoenfelder, Angele; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 239 - 249
反应条件
hydrazine hydrate in butan-1-ol T=100°C; 6 h;
参考文献
Wermuth, Camille-Georges; Bourguignon, Jean-Jacques; Schlewer, Gilbert; Gies, Jean-Pierre; Schoenfelder, Angele; et al.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 239 - 249
反应条件
triethyl amine hydrochloride in xylene 2 h; Heating / reflux;
参考文献
EP1719756 A1, ;
Page/Page column 43-44 ;
EP 1719756 A1
