3-氨基-6-(4-氯苯基)哒嗪合成路线 （共 5 条）
反应条件
tetrakis(triphenylphosphine) palladium(0); potassium carbonate in ethanol; water T=120°C; Suzuki coupling; 0.166667 h; Inert atmosphereSealed vialMicrowave irradiation;
参考文献
Gavande, Navnath; Johnston, Graham A. R.; Hanrahan, Jane R.; Chebib, Mary
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 18 p. 4131 - 4136
反应条件
hydrogen; nickel in methanol T=20°C; P=760 Torr;
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 2 p. 239 - 249
反应条件
sodium carbonate; tetrakis(triphenylphosphine) palladium(0) in toluene Arylation; Suzuki coupling reaction; 15 h; Heating;
参考文献
Maes, Bert U. W.; Lemiere, Guy L. F.; Dommisse, Roger; Augustyns, Koen; Haemers, Achiel
Tetrahedron, 2000 , vol. 56, # 12 p. 1777 - 1781
反应条件
1: phosphorus oxychloride / 4 h / 85 - 95 °C 2: hydrazine hydrate / butan-1-ol / 6 h / 100 °C 3: H2 / Raney Ni / methanol / 20 °C / 760 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 2 p. 239 - 249
反应条件
1: hydrazine hydrate / butan-1-ol / 6 h / 100 °C 2: H2 / Raney Ni / methanol / 20 °C / 760 Torr View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 30, # 2 p. 239 - 249
