6-甲基-异吲哚啉-1-酮合成路线 （共 3 条）
反应条件
1: With tert.-butyl lithium in tetrahydrofuran; n-heptane
T=0°C; 6 h; Inert atmosphere;
2: With water in tetrahydrofuran; pentane
T=0°C; 2 h; Inert atmosphere;
参考文献
Smith, Keith; El-Hiti, Gamal A.; Hegazy, Amany S.; Kariuki, Benson
Beilstein Journal of Organic Chemistry, 2011 , vol. 7, art. no. 142, p. 1219 - 1227
反应条件
1.1: triethylamine / dichloromethane / 0 - 20 °C
1.2: 0.25 h / 20 °C
2.1: didodecanoyl peroxide / 1,2-dichloro-ethane / 4 h / Reflux
3.1: trifluoroacetic acid / 0.5 h / Reflux
View Scheme
参考文献
Lopez-Valdez, German; Olguin-Uribe, Simon; Millan-Ortiz, Alejandra; Gamez-Montano, Rocio; Miranda, Luis D.
Tetrahedron, 2011 , vol. 67, # 14 p. 2693 - 2701
参考文献
de Diesbach
Helvetica Chimica Acta, 1940 , vol. 23, p. 1232,1252
