hydrogenchloride; platinum(IV) oxide; hydrogen in ethanol 42 h;

1: 94 percent / CHCl3 / 1.5 h / 100 °C 2: 99 percent / NEt3 / CH2Cl2 / 0.5 h / 0 - 5 °C 3: 92 percent / sodium azide / dimethylformamide / 1.5 h / 100 °C 4: 95 percent / hydrogen / 5percent Pd-C / ethyl acetate / 14 h 5: 72 percent / trifluoroacetic acid / 0.67 h / Ambient temperature View Scheme

1: 99 percent / NEt3 / CH2Cl2 / 0.5 h / 0 - 5 °C 2: 92 percent / sodium azide / dimethylformamide / 1.5 h / 100 °C 3: 95 percent / hydrogen / 5percent Pd-C / ethyl acetate / 14 h 4: 72 percent / trifluoroacetic acid / 0.67 h / Ambient temperature View Scheme

1: 95 percent / hydrogen / 5percent Pd-C / ethyl acetate / 14 h 2: 72 percent / trifluoroacetic acid / 0.67 h / Ambient temperature View Scheme

1: 92 percent / sodium azide / dimethylformamide / 1.5 h / 100 °C 2: 95 percent / hydrogen / 5percent Pd-C / ethyl acetate / 14 h 3: 72 percent / trifluoroacetic acid / 0.67 h / Ambient temperature View Scheme

trifluoroacetic acid 0.666667 h; Ambient temperature;

1: 72 percent / tetrahydrofuran / 17 h / Ambient temperature 2: 47 percent / PtO2, conc. HCl, hydrogen / ethanol / 42 h View Scheme