5-(2-溴苯基)-呋喃-2-甲醛合成路线 （共 5 条）
反应条件
hydrogenchloride; sodium nitrite in water
参考文献
Norwich Eaton Pharmaceuticals, Inc.
Patent: US4895867 A1, 1990 ;
反应条件
1: 1-Bromo-2-aminobenzene With hydrogenchloride; sodium nitrite in water T=0 - 5°C; 2: furfural in water T=10 - 40°C; Meerwein reaction;
参考文献
Puterova, Zita; Sterk, Heinz; Krutosikova, Alzbeta
Molecules, 2004 , vol. 9, # 1-2 p. 11 - 21
反应条件
hydroxylamine hydrochloride; sodium acetate in water
5 h; Heating;
参考文献
Pong; Pelosi Jr.; Wessels; Yu; Burns; White; Anthony Jr.; Ellis; Wright; White Jr.
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 10 p. 1411 - 1416
反应条件
1: 76 percent / NH2OH*HCl, anhydrous NaOAc / various solvent(s); H2O / 5 h / Heating
2: 47 percent / Ac2O / 3 h / Heating
View Scheme
参考文献
Pong; Pelosi Jr.; Wessels; Yu; Burns; White; Anthony Jr.; Ellis; Wright; White Jr.
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 10 p. 1411 - 1416
反应条件
1: 76 percent / NH2OH*HCl, anhydrous NaOAc / various solvent(s); H2O / 5 h / Heating
2: 47 percent / Ac2O / 3 h / Heating
3: 28 g / methanol / Ambient temperature
View Scheme
参考文献
Pong; Pelosi Jr.; Wessels; Yu; Burns; White; Anthony Jr.; Ellis; Wright; White Jr.
Arzneimittel-Forschung/Drug Research, 1983 , vol. 33, # 10 p. 1411 - 1416
