1: With bromine in diethyl ether
14 h; Heating;
2: With potassium hydroxide in methanol
48 h; Heating;
参考文献
Ohkata, Katsuo; Tamura, Yukiko; Shetuni, Brandon B.; Takagi, Ryukichi; Miyanaga, Wataru; Kojima, Satoshi; Paquette, Leo A.
Journal of the American Chemical Society, 2004 , vol. 126, # 51 p. 16783 - 16792
1.1: 80 percent / tosyl chloride; triethylamine; DMAP / CH2Cl2 / 26 h / 20 °C
2.1: bromine / diethyl ether / 14 h / Heating
2.2: 61 percent / KOH / methanol / 48 h / Heating; under N2
View Scheme
参考文献
Ohkata, Katsuo; Tamura, Yukiko; Shetuni, Brandon B.; Takagi, Ryukichi; Miyanaga, Wataru; Kojima, Satoshi; Paquette, Leo A.
Journal of the American Chemical Society, 2004 , vol. 126, # 51 p. 16783 - 16792
