7-羟基-1,2,3,4-四氢喹啉合成路线 （共 20 条）
反应条件
lithium aluminium tetrahydride in tetrahydrofuran Inert atmosphereCooling with iceReflux;
参考文献
Anzalone, Andrew V.; Wang, Tracy Y.; Chen, Zhixing; Cornish, Virginia W.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 2 p. 650 - 654
Angew. Chem., 2013 , vol. 125, # 2 p. 678 - 682,5
反应条件
boron tribromide in dichloromethane T=-78°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 13 p. 3415 - 3418
反应条件
potassium hydroxide elektrochemische Reduktion an einer Nickel-Kathode;
参考文献
Helvetica Chimica Acta, , vol. 32, p. 1278,1281
反应条件
hydrogen fluoride; dihydrogen peroxide; SbF5 T=-20°C; 0.166667 h;
参考文献
Tetrahedron Letters, , vol. 27, # 38 p. 4565 - 4568
反应条件
boron tribromide in dichloromethane T=-78 - 0°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 7 p. 1003 - 1008
反应条件
1: H2 / PtO2 / methanol / 3102.89 Torr 2: BBr3 / CH2Cl2 / -78 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 13 p. 3415 - 3418
反应条件
1: DMAP / tetrahydrofuran / Ambient temperature 2: 1.) LiAlH4, 2.) H2, AcOH / 2) Pd/C / 1.) from 0 deg C to RT, 2.) EtOAC, EtOH 3: BBr3 / CH2Cl2 / -78 - 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 7 p. 1003 - 1008
反应条件
1: polyphosphoric acid / 110 °C 2: DMAP / tetrahydrofuran / Ambient temperature 3: 1.) LiAlH4, 2.) H2, AcOH / 2) Pd/C / 1.) from 0 deg C to RT, 2.) EtOAC, EtOH 4: BBr3 / CH2Cl2 / -78 - 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 7 p. 1003 - 1008
反应条件
1: toluene / Heating 2: polyphosphoric acid / 110 °C 3: DMAP / tetrahydrofuran / Ambient temperature 4: 1.) LiAlH4, 2.) H2, AcOH / 2) Pd/C / 1.) from 0 deg C to RT, 2.) EtOAC, EtOH 5: BBr3 / CH2Cl2 / -78 - 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 7 p. 1003 - 1008
反应条件
1: 1.) LiAlH4, 2.) H2, AcOH / 2) Pd/C / 1.) from 0 deg C to RT, 2.) EtOAC, EtOH 2: BBr3 / CH2Cl2 / -78 - 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 7 p. 1003 - 1008
