4,4,4-三氟-1-(吡啶-3-基)-1,3-丁二酮合成路线 (共 1 条)
反应条件
1: With methanol; sodium T=0 - 20°C; 3 h; Heating / reflux; 2: With acetic acid in water pH=5; Product distribution / selectivity;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO. KG
Patent: WO2007/67836 A2, 2007 ;
Location in patent: Page/Page column 81-82 ;
WO 2007/067836 A2