4-溴-呋喃-2-甲酸甲酯合成路线 （共 7 条）
反应条件
ammonium chloride; zinc in methanol T=20°C; 2.5 h; Inert atmosphere;
参考文献
Brucoli, Federico; Natoli, Antonino; Marimuthu, Preethi; Borrello, Maria Teresa; Stapleton, Paul; Gibbons, Simon; Schaetzlein, Andreas
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 6 p. 2019 - 2024
反应条件
tris-(dibenzylideneacetone)dipalladium(0); trifuran-2-yl-phosphane; cesium fluoride in toluene T=100°C; Hiyama cross-coupling; 24 h; Inert atmosphere; regioselective reaction;
参考文献
Schweizer, Stefan A.; Bach, Thorsten
Synlett, 2010 , # 1 p. 81 - 84
反应条件
sulfuric acid 12 h; Reflux;
参考文献
Urbano, Mariangela; Guerrero, Miguel; Zhao, Jian; Velaparthi, Subash; Schaeffer, Marie-Therese; Brown, Steven; Rosen, Hugh; Roberts, Edward
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 18 p. 5470 - 5474
反应条件
1: ammonium hydroxide; zinc / water / 3 h / 20 °C 2: sulfuric acid / 12 h / Reflux View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 18 p. 5470 - 5474
反应条件
1: AlCl3, aluminium chloride; bromine / 1 h / 0 °C / Inert atmosphere 2: ammonium chloride; zinc / methanol / 2.5 h / 20 °C / Inert atmosphere View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 6 p. 2019 - 2024
反应条件
sodium tetrahydroborate; hydrogen; sodium hydrogencarbonate; palladium in methanol; benzene T=20°C; Rate constant;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , vol. 18, # 2 p. 134 - 138
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 18, # 2 p. 176 - 180
反应条件
tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide T=80°C; Inert atmosphere;
参考文献
Hawker, Dustin D.; Silverman, Richard B.
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 19 p. 5763 - 5773
