hydrogenchloride; acetic acid; pyridinium chlorochromate 1) CH2Cl2, 20 deg C, 12 h; 2) MeOH, 0 deg C, 1 h; 3) CH2Cl2 / 6h; Yield given. Multistep reaction. Yields of byproduct given;

1: 63 percent / Ti(OMe)4, TiCl4 / CH2Cl2 / 10 h / -40 °C 2: MeONa / methanol / 0.17 h / Ambient temperature 3: CDCl3; methanol 4: 1) BuLi, HMPT / 1) THF, hexane, -78 deg C, 10 min.; 2) THF, a) -78 deg C, 3 h, b) -30 deg C, 20 h 5: 90 percent / MeONa / methanol; tetrahydrofuran / 240 h / Ambient temperature View Scheme

2: Ag2O 4: oxidation View Scheme

Yield given. Multistep reaction. Yields of byproduct given;

hydrogenchloride; acetic acid; pyridinium chlorochromate 1) CH2Cl2, 20 deg C, 12 h; 2) MeOH, 0 deg C, 1 h; 3) CH2Cl2 / 6h; Yield given. Multistep reaction. Yields of byproduct given;

1: 70 percent / zinc chloride / acetonitrile / 0.83 h / Heating 2: 84 percent / t-BuOK / tetrahydrofuran / 1.) -70 deg C, 110 min., 2.) 0 deg C, 1 h., 3.) room temp., 90 min. 3: 1.) ionol 2.) 48percent HBr / 1.) acetone, reflux, 1 min., 2.) 40 min., reflux, acetone View Scheme

1: 60 percent / ZnCl2 / ethyl acetate / 1 h / 20 °C 2: 81 percent / sodium bis(2-methoxyethoxy)aluminum hydride / toluene / 1 h / 0 - 5 °C 3: (-)-DIPT; Ti(Oi-Pr)4; t-BuOOH / CH2Cl2 / 8 h / -20 °C 4: 87 percent / Ti(Oi-Pr)4 / benzene / 2 h / 80 °C 5: 84 percent / HCl / ethanol / 0.5 h / 20 °C 6: 76 percent / pyridine / 3 h / 0 °C 7: 64 percent / trimethylsilyl triflate / acetonitrile / 16 h / 20 °C 8: 22 percent / CH3ONa / methanol / 4 h / 20 °C View Scheme

暂无反应条件数据

暂无反应条件数据

bis-[(trifluoroacetoxy)iodo]benzene in dichloromethane T=20°C; 2 h; Further byproducts given;