4-(三氟甲基)苯甲酸乙酯合成路线 （共 49 条）
反应条件
N,N,N',N,-tetramethylethylenediamine; tetrabutylammomium bromide in N,N-dimethyl-formamide cathode: stainless steel, anode: copper; 1.) RT, 20 min, 3 bar, 2.) 95 deg C, 9 h, 10-15 bar;
参考文献
Paratian, J. M.; Sibille, S.; Perichon, J.
Journal of the Chemical Society, Chemical Communications, 1992 , # 1 p. 53 - 54
反应条件
in N,N-dimethyl-formamide T=110°C; 18 h; Inert atmosphere;
参考文献
Morimoto, Hiroyuki; Tsubogo, Tetsu; Litvinas, Nichole D.; Hartwig, John F.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 16 p. 3793 - 3798
反应条件
in N,N-dimethyl-formamide T=50°C; 18 h; Inert atmosphere;
参考文献
Morimoto, Hiroyuki; Tsubogo, Tetsu; Litvinas, Nichole D.; Hartwig, John F.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 16 p. 3793 - 3798
反应条件
Titanium(IV) oxide; trifluoroacetic acid in acetonitrile 24 h; Ambient temperatureIrradiation; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of the Chemical Society - Series Chemical Communications, , # 17 p. 1359 - 1361
反应条件
1: SOCl2 / Heating 2: Py / Heating View Scheme
参考文献
Canadian Journal of Chemistry, , vol. 48, p. 125 - 132
反应条件
in acetic acid 1 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 753 - 759
反应条件
lithium aluminium tetrahydride
参考文献
Dust, Julian M.; Arnold, Donald R.
Journal of the American Chemical Society, 1983 , vol. 105, # 5 p. 1221 - 1227
反应条件
water; potassium hydroxide T=115°C; 1 h;
参考文献
Kremlev, Mikhail M.; Tyrra, Wieland; Mushta, Aleksej I.; Naumann, Dieter; Yagupolskii, Yurii L.
Journal of Fluorine Chemistry, 2010 , vol. 131, # 2 p. 212 - 216
反应条件
1: With sodium diisobutyl-tert-butoxyaluminium hydride in tetrahydrofuran T=-70 - 0°C; 4 h; Inert atmosphere; 2: With ammonium hydroxide; iodine in tetrahydrofuran T=0 - 20°C; 2 h; Inert atmosphere;
参考文献
Miyagi, Kotaro; Moriyama, Katsuhiko; Togo, Hideo
European Journal of Organic Chemistry, 2013 , # 26 p. 5886 - 5892
参考文献
Li, Yan; Liu, Jie; Zhang, Hongquan; Yang, Xiangping; Liu, Zhaojie
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 8 p. 2278 - 2282
