3-氨基-4,6-二甲基噻吩并[2,3-b]吡啶-2-羧酸合成路线 （共 9 条）
反应条件
sodium hydroxide in ethanol 4 h; Heating;
参考文献
Journal of the Chinese Chemical Society, , vol. 48, # 6 B p. 1163 - 1174
反应条件
1: KOH 2: aq. KOH View Scheme
参考文献
Farmaco, Edizione Scientifica, , vol. 31, # 1 p. 21 - 30
反应条件
acetic acid in water
参考文献
Pharmazie, , vol. 45, # 2 p. 102 - 109
反应条件
(i) KOH, EtOH, (ii) /BRN= 605438/; Multistep reaction;
参考文献
Journal fuer Praktische Chemie (Leipzig), , vol. 316, p. 1030 - 1036
反应条件
1: 80 percent / DCC / pyridine / 20 h / Ambient temperature 2: 83 percent / NH2NH2 / dioxane / 6 h / Heating View Scheme
参考文献
Wagner; Vieweg; Leistner; Bohm; Krasselt; Hanfe ld; Prantz; Grupe
Pharmazie, 1990 , vol. 45, # 2 p. 102 - 109
反应条件
1: 80 percent / DCC / pyridine / 20 h / Ambient temperature 2: Pyridin, NaOH / H2O / 4 h / Heating View Scheme
参考文献
Wagner; Vieweg; Leistner; Bohm; Krasselt; Hanfe ld; Prantz; Grupe
Pharmazie, 1990 , vol. 45, # 2 p. 102 - 109
反应条件
1: 85 percent / pyridine / 5 h / Heating
2: hydrazine hydrate / ethanol / 3 h / Heating
View Scheme
参考文献
Ho, Yuh-Wen
Journal of the Chinese Chemical Society, 2001 , vol. 48, # 6 B p. 1163 - 1174
反应条件
1: 85 percent / pyridine / 5 h / Heating
2: hydrazine hydrate / ethanol / 3 h / Heating
3: 85 percent / acetic acid / 3 h / Heating
View Scheme
参考文献
Ho, Yuh-Wen
Journal of the Chinese Chemical Society, 2001 , vol. 48, # 6 B p. 1163 - 1174
参考文献
Guerrera; Siracusa; Tornetta
Farmaco, Edizione Scientifica, 1976 , vol. 31, # 1 p. 21 - 30
