反应条件
1: piperonal With n-butyllithium; N,N,N'-trimethyl-ethylenediamine in tetrahydrofuran
T=-78°C; 1 h;
2: methyl iodide in tetrahydrofuran
T=-78 - 20°C;
参考文献
Song, Yunlong; Shao, Zhiyu; Dexheimer, Thomas S.; Scher, Evan S.; Pommier, Yves; Cushman, Mark
Journal of Medicinal Chemistry, 2010 , vol. 53, # 5 p. 1979 - 1989
