3-氨基-4,4,4-三氟丁酸合成路线 （共 5 条）
反应条件
ammonia T=100°C; 20 h;
参考文献
Bevilacqua; Keith; Roberts
Journal of Organic Chemistry, 1984 , vol. 49, # 8 p. 1430 - 1434
反应条件
hydrogenchloride T=100°C; 6 h; Yield given;
参考文献
Tetrahedron Letters, , vol. 34, # 22 p. 3621 - 3624
反应条件
hydrogenchloride in 1,4-dioxane Ambient temperature;
参考文献
Xue, Chu-Biao; Roderick, John; Jackson, Sharon; Rafalski, Maria; Rockwell, Arlene; Mousa, Shaker; Olson, Richard E.; DeGrado, William F.
Bioorganic and Medicinal Chemistry, 1997 , vol. 5, # 4 p. 693 - 705
反应条件
in benzene
0.5 h; Ambient temperature;
参考文献
Bevilacqua; Keith; Roberts
Journal of Organic Chemistry, 1984 , vol. 49, # 8 p. 1430 - 1434
反应条件
1: With chloro-trimethyl-silane; TEA
2: With methylmagnesium bromide
参考文献
Jiang, Jinlong; Shah, Hemal; DeVita, Robert J.
Organic Letters, 2003 , vol. 5, # 22 p. 4101 - 4103
