1-溴-4-(甲氧基甲氧基)-2-甲基苯合成路线 （共 3 条）
反应条件
diisopropylamine in dichloromethane
T=0 - 20°C; 120 h;
参考文献
Kissei Pharmaceutical Co., Ltd.
Patent: EP1544208 A1, 2005 ;
Location in patent: Page/Page column 59-60 ;
反应条件
phosphorous pentoxide in dichloromethane
T=20°C; 3 h; Inert atmosphere;
参考文献
Hori, Yuichiro; Nakaki, Kyohei; Sato, Motoki; Mizukami, Shin; Kikuchi, Kazuya
Angewandte Chemie - International Edition, 2012 , vol. 51, # 23 p. 5611 - 5614
反应条件
n-butyllithium in tetrahydrofuran; hexane
T=-78 - 0°C; 1 h;
参考文献
Kissei Pharmaceutical Co., Ltd.
Patent: EP1544208 A1, 2005 ;
Location in patent: Page/Page column 59 ;
