2-甲酸基-2-苯基乙腈合成路线 （共 36 条）
反应条件
1: 88 percent / pyridine / 15 - 30 °C 2: 10 percent / carbon-sulphur cathode / dimethylformamide / electrolysis in NaClO4 electrolyte, H cell, graphite bar anode View Scheme
参考文献
Guillanton, Georges le; Do, Quang Tho; Simonet, Jacques
Bulletin de la Societe Chimique de France, 1989 , # 3 p. 433 - 440
反应条件
ammonium hydroxide; hydrazine hydrate; acetic acid in benzene
参考文献
Otsuka Pharmaceutical Company, Limited
Patent: US4824834 A1, 1989 ;
反应条件
potassium cyanide Erhitzen des Reaktionsprodukts mit wss. Schwefelsaeure und Essigsaeure;
参考文献
Hein
Journal of the American Chemical Society, 1955 , vol. 77, p. 2797,2800
参考文献
Walther; Schickler
Journal fuer Praktische Chemie (Leipzig), 1897 , vol. <2> 55, p. 323
反应条件
1: 80 percent / N-methylmorpholine / CH2Cl2 / 2 h / Ambient temperature 2: 1.) CH3ONa / 1.) CH3OH, 30 min, 10 deg C, 2.) CH3OH, reflux, 6 h View Scheme
参考文献
Jourdan; Laduree; Robba
Journal of Heterocyclic Chemistry, 1994 , vol. 31, # 2 p. 305 - 312
反应条件
1: phosphorus oxychloride 2: sulfuric acid View Scheme
参考文献
Ghosh
Journal of the Chemical Society, 1916 , vol. 109, p. 117
反应条件
hydrogenchloride; diethyl ether; zinc(II) chloride Erhitzen des Reaktionsprodukts mit wss. Schwefelsaeure;
参考文献
Badhwar et al.
Journal of the Chemical Society, 1931 , p. 1541,1543
反应条件
diethyl ether; zinc(II) chloride Einleiten von Chlorwasserstoff und Erhitzen des Reaktionsprodukts mit wss. Schwefelsaeure;
参考文献
Baker
Priv.-Mitt.
Full Text Show Details
Ghosh
Journal of the Chemical Society, 1916 , vol. 109, p. 117
反应条件
hydrazine hydrate in 1,4-dioxane; methanol T=140°C; 0.166667 h;
参考文献
Wilson, Noel S.; Osuma, Augustine T.; Camp, Jennifer A.Van; Xu, Xiangdong
Tetrahedron Letters, 2012 , vol. 53, # 34 p. 4498 - 4501
反应条件
ethanol; nickel T=50 - 70°C; P=73550.8 - 110326 Torr; Hydrogenation;
参考文献
Keller
Helvetica Chimica Acta, 1937 , vol. 20, p. 436,443
