2-羟基-3-三氟甲基喹噁啉合成路线 （共 7 条）
反应条件
in water T=50°C; 0.25 h;
参考文献
Murthy, Sabbavarapu Narayana; Madhav, Bandaru; Nageswar, Yadavalli Venkata Durga
Helvetica Chimica Acta, 2010 , vol. 93, # 6 p. 1216 - 1220
反应条件
sodium hydrogencarbonate in diethyl ether T=25°C; Cyclization; 3 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 15 p. 1729 - 1731
反应条件
in 1,4-dioxane 1.5 h; Heating;
参考文献
Mustafa, Mohamed El-Said; Takaoka, Akio; Ishikawa, Nobuo
Bulletin de la Societe Chimique de France, 1986 , # 6 p. 944 - 954
反应条件
in diethyl ether T=20°C; 12 h;
参考文献
Tyutin, V. Y.; Chkanikov, N. D.; Kolomietz, A. F.; Fokin, A. V.
Journal of Fluorine Chemistry, 1991 , vol. 51, # 3 p. 323 - 334
反应条件
in methanol 4 h; Heating;
参考文献
Burgart; Kuzueva; Kodess; Saloutin
Russian Journal of Organic Chemistry, 1998 , vol. 34, # 3 p. 375 - 380
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 8 p. 2457 - 2467
反应条件
phosphorus pentachloride; trichlorophosphate 1 h; Reflux;
参考文献
Smits, Rogier A.; Lim, Herman D.; Hanzer, Agnes; Zuiderveld, Obbe P.; Guaita, Elena; Adami, Maristella; Coruzzi, Gabriella; Leurs, Rob; De Esch, Iwan J. P.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 8 p. 2457 - 2467
