(S)-2-N-Cbz-3-N-Boc-丙酸甲酯合成路线 (共 22 条)
反应条件
1: 1.) CF3COOH / 1.) CH2Cl2, RT, 20 min, 2.) H2O, RT, 1 h 2: 344 mg / CF3COOH, triethylsilane / CHCl3 / 14 h / Ambient temperature View Scheme
参考文献
Sakai; Ohfune
Journal of the American Chemical Society, 1992 , vol. 114, # 3 p. 998 - 1010
反应条件
1: With lithium hydroxide; water in tetrahydrofuran T=20°C; 1.5 h; 2: With citric acid in water; ethyl acetate
参考文献
EP1577302 A1, ;
Page/Page column 222-223 ;