拉凡醇; 5-甲基-2-(1-甲基乙烯基)-4-己烯-1-醇合成路线 （共 65 条）
反应条件
lithium aluminium tetrahydride in diethyl ether T=0 - 20°C; 1.33333 h; Inert atmosphere;
参考文献
Pepper, Henry P.; Tulip, Stephen J.; Nakano, Yuji; George, Jonathan H.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2564 - 2573
反应条件
lithium triethylborohydride in tetrahydrofuran 18 h; Ambient temperature;
参考文献
Majewski, M.; Mpango, G. B.; Thomas, M. T.; Wu, A.; Snieckus, V.
Journal of Organic Chemistry, 1981 , vol. 46, # 10 p. 2029 - 2045
反应条件
sodium tetrahydroborate in ethanol 4 h; Ambient temperature;
参考文献
Mino; Fukui; Yamashita
Journal of Organic Chemistry, 1997 , vol. 62, # 3 p. 734 - 735
反应条件
potassium hydrogensulfate T=65 - 70°C; P=1 Torr; destillation;
参考文献
Babin, Didier; Fourneron, Jean-Dominique; Julia, Marc
Bulletin de la Societe Chimique de France, 1980 , vol. 2, # 11-12 p. 588 - 600
反应条件
lithium; ethylamine; tert-butyl alcohol in tetrahydrofuran T=-78°C; 0.166667 h;
参考文献
Araki, Shuki; Kambe, Shinya; Kameda, Keiko; Hirashita, Tsunehisa
Synthesis, 2003 , # 5 p. 751 - 754
反应条件
1.1: 79 percent / N,N'-dimethylimidazolidinone; H2O; InI / Pd(Ph3P)4 / 48 h / 20 °C 2.1: 77 percent / DMAP / CH2Cl2 / 24 h / 20 °C 3.1: HCO2H; Et3N / Pd(Ph3P)4 / tetrahydrofuran / 7 h / 20 °C 3.2: NaOH / tetrahydrofuran; methanol / 15 h / 20 °C View Scheme
参考文献
Synthesis, , # 5 p. 751 - 754
反应条件
1: 95 percent / LDA / tetrahydrofuran / -78 °C 2: 63 percent / H2O, 10percent HCl / acetonitrile / 6 h / 50 °C 3: hydrure de lithium aluminium / diethyl ether / 1.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 40, # 9 p. 1573 - 1580
反应条件
copper(l) chloride; tin(ll) chloride in water; isopropyl alcohol T=50°C; 15 h;
参考文献
Imai, Toshiro; Nishida, Shinya
Journal of the Chemical Society, Chemical Communications, 1994 , # 3 p. 277 - 278
反应条件
lithium triethylborohydride; [1,4-bis-(diphenylphosphine)butane]palladium (II) dichloride; triphenyl silane in tetrahydrofuran T=20°C; 0.05 h; Yield given. Yields of byproduct given;
参考文献
Chemistry Letters, , p. 707 - 710
反应条件
1: With n-butylzinc chloride; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran 2 h; Heating; 2: With sodium hydroxide in tetrahydrofuran; methanol T=20°C; 15 h; Title compound not separated from byproducts;
参考文献
Synthesis, , # 5 p. 751 - 754
