拉凡醇; 5-甲基-2-(1-甲基乙烯基)-4-己烯-1-醇合成路线 （共 65 条）
反应条件
potassium hydroxide in ethanol 3 h; Ambient temperature;
参考文献
Fleming, Ian; Lee, Duckhee
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 17 p. 2701 - 2709
反应条件
1: With formic acid; triethylamine; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=20°C; 7 h; 2: With sodium hydroxide in tetrahydrofuran; methanol T=20°C; 15 h; Title compound not separated from byproducts;
参考文献
Synthesis, , # 5 p. 751 - 754
反应条件
1: 10 percent / N,N'-dimethylimidazolidinone; H2O; InI / Pd(Ph3P)4 / 48 h / 20 °C 2: 85 percent / DMAP / pyridine / 1 h / 20 °C 3: 56 percent / Li; EtNH2; t-BuOH / tetrahydrofuran / 0.17 h / -78 °C View Scheme
参考文献
Synthesis, , # 5 p. 751 - 754
反应条件
1: 85 percent / DMAP / pyridine / 1 h / 20 °C 2: 56 percent / Li; EtNH2; t-BuOH / tetrahydrofuran / 0.17 h / -78 °C View Scheme
参考文献
Synthesis, , # 5 p. 751 - 754
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 5 h; Ambient temperature;
参考文献
Fleming, Ian; Lee, Duckhee
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 17 p. 2701 - 2709
反应条件
1.1: 77 percent / DMAP / CH2Cl2 / 24 h / 20 °C 2.1: HCO2H; Et3N / Pd(Ph3P)4 / tetrahydrofuran / 7 h / 20 °C 2.2: NaOH / tetrahydrofuran; methanol / 15 h / 20 °C View Scheme
参考文献
Synthesis, , # 5 p. 751 - 754
反应条件
water; dihydrogen peroxide; sodium hydrogencarbonate in tetrahydrofuran; methanol 12 h; Heating;
参考文献
Fleming, Ian; Lee, Duckhee
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 17 p. 2701 - 2709
反应条件
(2,6-di-tert-butyl-4-methylphenoxy)methylaluminum trifluoromethanesulfonate in dichloromethane T=25°C; 1.5 h; Yield given;
参考文献
Tetrahedron Letters, , vol. 23, # 18 p. 1933 - 1936
反应条件
1: 93 percent / n-BuLi 2: LiBH4 / 5 mol percent <(PdCl2(PPh3)2> / tetrahydrofuran / 8 h / -45 °C View Scheme
参考文献
Chemistry Letters, , p. 707 - 710
反应条件
1: 1.) diisopropylamine, n-BuLi / 1.) a.) THF, 0 deg C, 1 h, b.) 30-35 deg C, 0.5 h, 2.) 0 deg C to RT, 4 h 2: 93 percent / lithium triethylborohydride / tetrahydrofuran / 18 h / Ambient temperature View Scheme
参考文献
Journal of Organic Chemistry, , vol. 46, # 10 p. 2029 - 2045
