拉凡醇; 5-甲基-2-(1-甲基乙烯基)-4-己烯-1-醇合成路线 （共 65 条）
反应条件
1: 63 percent / H2O, 10percent HCl / acetonitrile / 6 h / 50 °C 2: hydrure de lithium aluminium / diethyl ether / 1.5 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 40, # 9 p. 1573 - 1580
反应条件
lithium aluminium tetrahydride in diethyl ether 1.5 h; Ambient temperature; Yield given;
参考文献
Tetrahedron, , vol. 40, # 9 p. 1573 - 1580
反应条件
hydrogenchloride; potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate 1.) MeOH, THF, RT, 3 h, 2.) reflux, 12 h; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 37, # 38 p. 6929 - 6930
反应条件
1: 85 percent / sodium bis(trimethylsilyl)amide / tetrahydrofuran; toluene / 0.5 h / Heating 2: 96 percent / HCl, KF, MeOH / CH2Cl2 / 2 h / Ambient temperature 3: 59 percent / H2O2, NaHCO3, H2O / methanol; tetrahydrofuran / 12 h / Heating View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 17 p. 2701 - 2709
反应条件
2: 80 percent / diethyl ether; tetrahydrofuran / 24 h / Ambient temperature 3: 80 percent / HCl, MeOH / CH2Cl2 / 0.02 h / Ambient temperature 4: 70 percent / H2O2, H2O, KF, KHCO3 / tetrahydrofuran; methanol / 0.33 h / Ambient temperature 5: 69 percent / Et3N, DMAP / CH2Cl2 / 48 h / Ambient temperature 6: 24 percent / PCl3, DMF, pyridine / tetrahydrofuran / 1 h / Ambient temperature 7: 67 percent / TBAF / tetrahydrofuran / 5 h / Ambient temperature View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 17 p. 2701 - 2709
反应条件
1: 78 percent / tetrahydrofuran / 4 h / -5 - 10 °C 2: CuCl2, CuO / acetone / 1 h / Heating 3: hydrure de lithium aluminium / diethyl ether / 3 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 40, # 9 p. 1573 - 1580
反应条件
1: CuCl2, CuO / acetone / 1 h / Heating 2: hydrure de lithium aluminium / diethyl ether / 3 h / Ambient temperature View Scheme
参考文献
Tetrahedron, , vol. 40, # 9 p. 1573 - 1580
反应条件
1: acetonitrile / 96 h 2: 39 percent / HCl / tetrahydrofuran; H2O / 5.5 h / 75 °C 3: 13 mg / NaBH4, EtOH / ethanol / 1.) 0 deg C, 15 min then rt., 45 min View Scheme
参考文献
Tetrahedron, , vol. 41, # 24 p. 5741 - 5746
反应条件
1: 39 percent / HCl / tetrahydrofuran; H2O / 5.5 h / 75 °C 2: 13 mg / NaBH4, EtOH / ethanol / 1.) 0 deg C, 15 min then rt., 45 min View Scheme
参考文献
Tetrahedron, , vol. 41, # 24 p. 5741 - 5746
反应条件
1: NBS / CCl4 / Irradiation 2: K2CO3 / tetrahydrofuran / 8 h / Ambient temperature 3: 1.) n-Bu2CuLi / 1.) THF, -30 deg C, 20 min, 2.) 30 min 4: 95 percent / LiAlH4 View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 120, # 3 p. 203 - 205
