1-苄基吡咯烷-2,3-二酮合成路线 （共 8 条）
反应条件
oxygen; rose bengal in dichloromethane
T=-78°C; 1 h; Irradiation;
参考文献
Wasserman, Harry H.; Ives, Jeffrey L.
Journal of Organic Chemistry, 1985 , vol. 50, # 19 p. 3573 - 3580
反应条件
water; trifluoroacetic acid
T=20°C; Hydrolysis;
参考文献
Jungf, Alexander; Koch, Oliver; Ries, Monika; Schaumann, Ernst
Synlett, 2000 , # 1 p. 92 - 94
反应条件
hydrogenchloride; water
参考文献
Southwick; Crouch
Journal of the American Chemical Society, 1953 , vol. 75, p. 3413,3416
反应条件
1: 93 percent / KH / tetrahydrofuran / 0 - 20 °C
2: 88 percent / bis(trifluoroacetoxy)iodobenzene / 20 °C
3: 97 percent / TFA; H2O / 20 °C
View Scheme
参考文献
Jungf, Alexander; Koch, Oliver; Ries, Monika; Schaumann, Ernst
Synlett, 2000 , # 1 p. 92 - 94
反应条件
hydrogenchloride
0.333333 h; Heating;
参考文献
Baldwin; Chan; Gallacher; Otsuka
Tetrahedron, 1984 , vol. 40, # 21 p. 4513 - 4525
反应条件
1: 88 percent / bis(trifluoroacetoxy)iodobenzene / 20 °C
2: 97 percent / TFA; H2O / 20 °C
View Scheme
参考文献
Jungf, Alexander; Koch, Oliver; Ries, Monika; Schaumann, Ernst
Synlett, 2000 , # 1 p. 92 - 94
反应条件
1: 2.)NaOMe / 1) MeOH, 24 h, 25 deg C, 2) MeOH, reflux, 1 h
2: 20percent HCl / 0.33 h / Heating
View Scheme
参考文献
Baldwin; Chan; Gallacher; Otsuka
Tetrahedron, 1984 , vol. 40, # 21 p. 4513 - 4525
反应条件
ethanol; platinum
Hydrogenation;
参考文献
Southwick et al.
Journal of Organic Chemistry, 1956 , vol. 21, p. 1087,1092
