(5-(4-甲氧基苯基)异噁唑-3-基)甲醇合成路线 (共 8 条)
反应条件
sodium tetrahydroborate in tetrahydrofuran; ethanol T=0°C; 4 h;
参考文献
European Journal of Pharmaceutical Sciences, , vol. 42, # 3 p. 180 - 191
反应条件
1: hydroxylamine hydrochloride / ethanol / 6 h / Reflux 2: sodium tetrahydroborate / tetrahydrofuran; ethanol / 4 h / 0 °C View Scheme
参考文献
European Journal of Pharmaceutical Sciences, , vol. 42, # 3 p. 180 - 191
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.17 h / 0 °C / Inert atmosphere 1.2: 3 h / 20 °C / Inert atmosphere 2.1: hydroxylamine hydrochloride / ethanol / 6 h / Reflux 3.1: sodium tetrahydroborate / tetrahydrofuran; ethanol / 4 h / 0 °C View Scheme
参考文献
European Journal of Pharmaceutical Sciences, , vol. 42, # 3 p. 180 - 191
反应条件
manganese(IV) oxide in chloroform T=20°C; 24 h;
参考文献
Akbarzadeh, Tahmineh; Rafinejad, Ali; Mollaghasem, Javad Malekian; Safavi, Maliheh; Fallah-Tafti, Asal; Pordeli, Mahboobeh; Ardestani, Sussan Kabudanian; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 386 - 392
反应条件
sodium tetrahydroborate in tetrahydrofuran; ethanol
T=0°C; 4 h;
参考文献
Lopopolo, Gianfranco; Fiorella, Filomena; De Candia, Modesto; Nicolotti, Orazio; Martel, Sophie; Carrupt, Pierre-Alain; Altomare, Cosimo
European Journal of Pharmaceutical Sciences, 2011 , vol. 42, # 3 p. 180 - 191
反应条件
1: hydroxylamine hydrochloride / ethanol / 6 h / Reflux
2: sodium tetrahydroborate / tetrahydrofuran; ethanol / 4 h / 0 °C
View Scheme
参考文献
Lopopolo, Gianfranco; Fiorella, Filomena; De Candia, Modesto; Nicolotti, Orazio; Martel, Sophie; Carrupt, Pierre-Alain; Altomare, Cosimo
European Journal of Pharmaceutical Sciences, 2011 , vol. 42, # 3 p. 180 - 191
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 0.17 h / 0 °C / Inert atmosphere
1.2: 3 h / 20 °C / Inert atmosphere
2.1: hydroxylamine hydrochloride / ethanol / 6 h / Reflux
3.1: sodium tetrahydroborate / tetrahydrofuran; ethanol / 4 h / 0 °C
View Scheme
参考文献
Lopopolo, Gianfranco; Fiorella, Filomena; De Candia, Modesto; Nicolotti, Orazio; Martel, Sophie; Carrupt, Pierre-Alain; Altomare, Cosimo
European Journal of Pharmaceutical Sciences, 2011 , vol. 42, # 3 p. 180 - 191
反应条件
manganese(IV) oxide in chloroform
T=20°C; 24 h;
参考文献
Akbarzadeh, Tahmineh; Rafinejad, Ali; Mollaghasem, Javad Malekian; Safavi, Maliheh; Fallah-Tafti, Asal; Pordeli, Mahboobeh; Ardestani, Sussan Kabudanian; Shafiee, Abbas; Foroumadi, Alireza
Archiv der Pharmazie, 2012 , vol. 345, # 5 p. 386 - 392