(4S)-4alpha-乙基-4-羟基-7-氨基-1H-吡喃并[3',4':6,7]吲哚嗪并[1,2-b]喹啉-3,14(4H,12H)-二酮合成路线 （共 2 条）
反应条件
hydrogen; platinum(IV) oxide in 1,4-dioxane; ethanol
P=760 Torr; 2 h;
参考文献
Sawada; Matsuoka; Nokata; Nagata; Furuta; Yokokura; Miyasaka
Chemical and Pharmaceutical Bulletin, 1991 , vol. 39, # 12 p. 3183 - 3188
反应条件
1: 41 percent / conc. H2SO4, HNO3 / 0.5 h / 0 °C
2: 82 percent / conc. HCl, Sn, SnCl2*2H2O / ethanol / 1.5 h / -7 °C
View Scheme
参考文献
Wani; Nicholas; Wall
Journal of Medicinal Chemistry, 1986 , vol. 29, # 11 p. 2358 - 2363
