1: With toluene-4-sulfonic acid in toluene T=110°C; 4 h; 2: With hydrogenchloride in water pH=7;

1.1: 3-chloro-benzenecarboperoxoic acid / chloroform / 5 h / 20 °C / Inert atmosphere 1.2: pH 7 2.1: 144 h / 20 °C / Inert atmosphere 3.1: ethanol; water / 0.83 h / 50 °C 3.2: Cooling with ice 4.1: ethanol; sodium tetrahydroborate / 72 h / 20 °C 5.1: hydrogenchloride / water / 100 °C 6.1: tetrahydrofuran / Reflux 7.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran 8.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C 8.2: pH 7 View Scheme

1.1: 144 h / 20 °C / Inert atmosphere 2.1: ethanol; water / 0.83 h / 50 °C 2.2: Cooling with ice 3.1: ethanol; sodium tetrahydroborate / 72 h / 20 °C 4.1: hydrogenchloride / water / 100 °C 5.1: tetrahydrofuran / Reflux 6.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran 7.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C 7.2: pH 7 View Scheme

1.1: ethanol; water / 0.83 h / 50 °C 1.2: Cooling with ice 2.1: ethanol; sodium tetrahydroborate / 72 h / 20 °C 3.1: hydrogenchloride / water / 100 °C 4.1: tetrahydrofuran / Reflux 5.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran 6.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C 6.2: pH 7 View Scheme

1.1: ethanol; sodium tetrahydroborate / 72 h / 20 °C 2.1: hydrogenchloride / water / 100 °C 3.1: tetrahydrofuran / Reflux 4.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran 5.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C 5.2: pH 7 View Scheme

1.1: hydrogenchloride / water / 100 °C 2.1: tetrahydrofuran / Reflux 3.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran 4.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C 4.2: pH 7 View Scheme

1.1: tetrahydrofuran / Reflux 2.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran 3.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C 3.2: pH 7 View Scheme

1.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran 2.1: toluene-4-sulfonic acid / toluene / 4 h / 110 °C 2.2: pH 7 View Scheme

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