1: .beta.-dibromonaphthaline With tert.-butyl lithium in tetrahydrofuran; pentane T=-78°C; Metallation; 2: carbon dioxide in tetrahydrofuran; pentane T=-78°C; Carboxylation;
参考文献
Katz, Thomas J.; Liu, Longbin; Willmore, Nikolaos D.; Fox, Joseph M.; Rheingold, Arnold L.; Shi, Shuhao; Nuckolls, Colin; Rickman, Barry H.
Journal of the American Chemical Society, 1997 , vol. 119, # 42 p. 10054 - 10063
1: With pyridine in 1-methyl-pyrrolidin-2-one
T=180°C; 1.66667 h;
2: With hydrogenchloride; anhydrous iron chloride in 1-methyl-pyrrolidin-2-one; water
T=80°C; 1 h;