(R)-(-)-2-氨基-1-丁醇合成路线 （共 29 条）
反应条件
1: With (2R,3S)-(-)-di-O-benzoyl tartaric acid in acetone T=25°C; 6 h; 2: With potassium hydroxide in dichloromethane
参考文献
Periasamy, Mariappan; Sivakumar, Sangarappan; Reddy, Meda Narsi
Synthesis, 2003 , # 13 p. 1965 - 1967
参考文献
Esswein, Angelika; Kling, Lothar; Leser, Ulrike; Friebe, Walter-Gunar
Patent: US6444832 B1, 2002 ;
反应条件
chiral stationary phase including isopropyl-functionalized CF6 in methanol; acetic acid; triethylamine; acetonitrile T=20°C; Purification / work up;
参考文献
WO2010/148191 A2, ;
Page/Page column 45-49; 59 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
参考文献
Journal of Organic Chemistry, , vol. 28, p. 1339 - 1342
反应条件
sodium hydroxide T=80°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 23 p. 5079 - 5082
反应条件
sodium hydroxide T=80°C; 2 h;
参考文献
Journal of Organic Chemistry, , vol. 52, # 23 p. 5079 - 5082
反应条件
lithium aluminium tetrahydride in diethyl ether
参考文献
Doklady Chemistry, , vol. 145, p. 597 - 600
Doklady Akademii Nauk SSSR, , vol. 145, p. 332 - 335
反应条件
methanol; Amberlyst 15; ammonia 1.) CH2Cl2, 25 deg C, 6 h, 2.) 50 min; Yield given. Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 63, # 10 p. 3471 - 3473
反应条件
in neat (no solvent) addn. of boron compd. to equimolar amt. of aminoalkanol, room temp.; driving out CH3NH2 in a stream of Ar, 20-25°C, 18h; distn. (vac.); elem. anal.; monocyclic : bicyclic isomer = 95:5;
参考文献
Chemische Berichte, , vol. 123, p. 2287 - 2302
参考文献
Radke et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 2801
