(S)-(-)-2-氨基-3-苄氧基-1-丙醇合成路线 (共 6 条)
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran 2 h; Reflux; 2: With sodium hydroxide in tetrahydrofuran; water T=20°C; 18 h;
参考文献
Sugimoto, Tomohiro; Tanikawa, Tetsuya; Suzuki, Keiko; Yamasaki, Yukiko
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 19 p. 5787 - 5801
反应条件
lithium aluminium tetrahydride in tetrahydrofuran T=0 - 20°C; Inert atmosphere;
参考文献
Borcard, Francoise; Baud, Matthias; Bello, Claudia; Dal Bello, Giovanna; Grossi, Francesco; Pronzato, Paolo; Cea, Michele; Nencioni, Alessio; Vogel, Pierre
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 17 p. 5353 - 5356
反应条件
1: With hydrogenchloride in water 2: With sodium hydroxide in water
参考文献
WO2003/99195 A2, ;
Page 58 ;
反应条件
1: SOCl2 2: NaBH4, CaCl2 / tetrahydrofuran 3: HCl View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 51, # 5 p. 1433 - 1440
反应条件
1: NaBH4, CaCl2 / tetrahydrofuran 2: HCl View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 51, # 5 p. 1433 - 1440
反应条件
sodium tetrahydroborate; sulfuric acid
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 9, # 15 p. 2273 - 2278