trimethylamine-N-oxide in tetrahydrofuran; chloroform 50 h; Ambient temperature;

tris-(dibenzylideneacetone)dipalladium(0); trifuran-2-yl-phosphane; cesium fluoride in toluene T=100°C; Hiyama cross-coupling; 24 h; Inert atmosphere; regioselective reaction;

tetrabutyl ammonium fluoride; tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=50°C; 2.5 h;