1: 3-methyl-2,6-dichloropyridine With N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 8 h; Reflux500 watt tungsten halogen lamp initiation; 2: potassium cyanide in ethanol T=40°C; 22.5 h; Reflux;

in ethanol; water T=80°C; 4 h; Inert atmosphere;

1: sodium tetrahydroborate / methanol / 0.5 h / 0 °C / Inert atmosphere 2: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 6 h / 0 - 25 °C / Inert atmosphere 3: ethanol; water / 4 h / 80 °C / Inert atmosphere View Scheme

1: thionyl chloride; N,N-dimethyl-formamide / dichloromethane / 6 h / 0 - 25 °C / Inert atmosphere 2: ethanol; water / 4 h / 80 °C / Inert atmosphere View Scheme