2-(叔丁氧羰基氧亚氨基)-2-苯乙腈合成路线 (共 188 条)
反应条件
triethylamine in water; acetone
参考文献
Ho, Bin; Michael Crider; Stables, James P
European Journal of Medicinal Chemistry, 2001 , vol. 36, # 3 p. 265 - 286
反应条件
triethylamine in tetrahydrofuran T=0 - 20°C; 5.5 h; Inert atmosphere;
参考文献
Macromolecules, , vol. 45, # 17 p. 7157 - 7162
反应条件
1: triethylamine / dioxane; H2O / 4 h / Ambient temperature 2: NaH / tetrahydrofuran / 24 h / Ambient temperature View Scheme
参考文献
Kajiyama, Shin-Ichiro; Irie, Kazuhiro; Kido, Takae; Koshimizu, Koichi; Hayashi, Hideo; Arai, Motoo
Tetrahedron, 1991 , vol. 47, # 29 p. 5453 - 5462
参考文献
Maeda; Kawasaki; Watanabe; Kaneto
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 3 p. 826 - 828
反应条件
TEA in 1,4-dioxane; methanol; water 3 h;
参考文献
Gomez-Vidal, Jose A.; Silverman, Richard B.
Organic Letters, 2001 , vol. 3, # 16 p. 2481 - 2484
参考文献
Maeda; Kawasaki; Watanabe; Kaneto
Chemical and Pharmaceutical Bulletin, 1989 , vol. 37, # 3 p. 826 - 828
反应条件
triethylamine in 1,4-dioxane; water 4 h; Ambient temperature;
参考文献
Kajiyama, Shin-Ichiro; Irie, Kazuhiro; Kido, Takae; Koshimizu, Koichi; Hayashi, Hideo; Arai, Motoo
Tetrahedron, 1991 , vol. 47, # 29 p. 5453 - 5462
反应条件
1: 87 percent / H2O; dioxane / 4 h / 20 °C 2: 68 percent / dicyclohexylcarbodiimide / tetrahydrofuran / 20 °C View Scheme
参考文献
Laurent, Sophie; Botteman, Francois; Vander Elst, Luce; Muller, Robert N.
Helvetica Chimica Acta, 2004 , vol. 87, # 5 p. 1077 - 1089
反应条件
hydrogenchloride; sodium hydroxide; potassium carbonate; dimethyl sulfate in 1,4-dioxane; dioxane - water; diethyl ether; acetone
参考文献
US6498165 B1, ;
US 6498165 B1
反应条件
triethylamine in water Ambient temperature;
参考文献
Jackson, Sharon; DeGrado, William; Dwivedi, Anil; Parthasarathy, Anju; Higley, Anne; Krywko, James; Rockwell, Arlene; Markwalder, Jay; Wells, Greg; Wexler, Ruth; Mousa, Shaker; Harlow, Richard
Journal of the American Chemical Society, 1994 , vol. 116, # 8 p. 3220 - 3230