2-(叔丁氧羰基氧亚氨基)-2-苯乙腈合成路线 （共 188 条）
参考文献
Tsunematsu; Aratani; Mizusaki; Hatanaka; Kawata; Yamamoto; Makisumi
Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 3 p. 1205 - 1209
→
119798-08-2(10S)-2,2,21,21-四甲基-4,19-二氧代-3,20-二氧杂-5,9,14,18-四氮杂二十二烷-9,10,14-三羧酸 9,14-二叔丁酯
参考文献
Li, Yanhong; Debs, Robert J.; Heath, Timothy D.
Synlett, 2006 , # 14 p. 2284 - 2286
反应条件
sodium hydroxide in water; N,N-dimethyl-formamide
Heating;
参考文献
Thaisrivongs; Pals; Lawson; Turner; Harris
Journal of Medicinal Chemistry, 1987 , vol. 30, # 3 p. 536 - 541
反应条件
triethylamine in tetrahydrofuran; water
2 h; Ambient temperature;
参考文献
Coulter, Carolyn V.; Gerrard, Juliet A.; Kraunsoe, James A. E.; Moore, Deborah J.; Pratt, Andrew J.
Tetrahedron, 1996 , vol. 52, # 20 p. 7127 - 7136
反应条件
in tetrahydrofuran
4 h;
参考文献
Bueno, G. Jimenez; Klimkait; Gilbert; Simons
Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 1 p. 87 - 94
反应条件
1: 69 percent / triethylamine / dioxane / Ambient temperature
2: 59 percent / 3-<3-(dimethylamino)propyl>-1-ethylcarbodiimide (DAEC) / propan-2-ol / Ambient temperature
3: triethylamine / various solvent(s) / 1.) 24 h, 0 deg C, 2.) room temperature, 24 h
View Scheme
参考文献
Phillips, Lawrence R.; Nishimura, Osamu; Fraser, Blair A.
Carbohydrate Research, 1984 , vol. 132, p. 275 - 286
反应条件
triethylamine in methanol
T=25°C; Acylation; 24 h;
参考文献
Saladino, Raffaele; Mezzetti, Maurizio; Mincione, Enrico; Torrini, Ines; Paradisi, Mario Paglialunga; Mastropietro, Gaia
Journal of Organic Chemistry, 1999 , vol. 64, # 23 p. 8468 - 8474
反应条件
triethylamine in water; acetone
参考文献
Crider; Tita; Wood; Hinko
Journal of Pharmaceutical Sciences, 1982 , vol. 71, # 11 p. 1214 - 1219
反应条件
1: 88 percent / triethylamine / dioxane; H2O; methanol / 4 h / 20 °C
2: DEAD; PPh3 / tetrahydrofuran
View Scheme
参考文献
Gomez-Vidal, Jose A.; Silverman, Richard B.
Organic Letters, 2001 , vol. 3, # 16 p. 2481 - 2484
反应条件
hydrogenchloride; sodium hydroxide in ethyl acetate
参考文献
ICI Americas Inc.
Patent: US4247549 A1, 1981 ;
