2-(叔丁氧羰基氧亚氨基)-2-苯乙腈合成路线 （共 188 条）
反应条件
triethylamine in 1,4-dioxane; water T=20°C; 24 h;
参考文献
Franchini; Corbo; Lentini; Bruno; Scilimati; Tortorella; Camerino; De Luca
Journal of Medicinal Chemistry, 2000 , vol. 43, # 20 p. 3792 - 3798
反应条件
triethylamine in tetrahydrofuran; methanol; water 2 h;
参考文献
Sibi, Mukund P.; Christensen, James W.
Tetrahedron Letters, 1995 , vol. 36, # 35 p. 6213 - 6216
参考文献
Elsworth, John F.; Msimang, Lorenzo N.; Jackson, Graham E.
South African Journal of Chemistry, 1999 , vol. 52, # 1 p. 44 - 48
反应条件
triethylamine in 1,4-dioxane; water 4 h; Ambient temperature;
参考文献
Kajiyama, Shin-Ichiro; Irie, Kazuhiro; Kido, Takae; Koshimizu, Koichi; Hayashi, Hideo; Arai, Motoo
Tetrahedron, 1991 , vol. 47, # 29 p. 5453 - 5462
反应条件
triethylamine 1.) DMF, 2 d, 2.) dioxan/water, 24 h;
参考文献
Van den Braken-Van Leersum; Maat
Recueil des Travaux Chimiques des Pays Bas, 1984 , vol. 103, # 4 p. 110 - 111
反应条件
potassium carbonate; triethylamine; palladium monocarbide in dichloromethane; acetic acid; toluene
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1104754 A1, 2001 ;
反应条件
1: Methyl 4-(1-methoxycarbonylpyrrolidin-3-yl)benzoate With hydrogenchloride in methanol; water 40 h; Heating / reflux; 2: 2-(tert-butoxycarbonyloxyimino)-2-phenylacetonitrile With N-ethyl-N,N-diisopropylamine in DMF (N,N-dimethyl-formamide) T=20°C; 15 h;
参考文献
DAIICHI PHARMACEUTICAL CO., LTD.
Patent: EP1577302 A1, 2005 ;
Location in patent: Page/Page column 124 ;
反应条件
1: 88 percent / triethylamine / dioxane; H2O; methanol / 4 h / 20 °C 2: 99 percent / methanol; diethyl ether / 0.25 h / 20 °C View Scheme
参考文献
Gomez-Vidal, Jose A.; Silverman, Richard B.
Organic Letters, 2001 , vol. 3, # 16 p. 2481 - 2484
参考文献
Chatterjee, Sankar; Dunn, Derek; Mallya, Satish; Ator, Mark A.
Bioorganic and Medicinal Chemistry Letters, 1999 , vol. 9, # 17 p. 2603 - 2606
反应条件
triethylamine in tetrahydrofuran 3 h;
参考文献
SK Corporation
Patent: EP1149079 B1, 2004 ;
Location in patent: Page 16-17 ;
