(Z)-3,4’,5-三甲氧基-3’-(叔-丁基二甲基硅烷基氧基)二苯乙烯合成路线 （共 5 条）
反应条件
1: (3,5-dimethoxybenzyl)triphenylphosphonium bromide With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 2 h; 2: 3-(tert-butyldimethylsilanyloxy)-4-methoxybenz-aldehyde in tetrahydrofuran; hexane T=20°C;
参考文献
Journal of Medicinal Chemistry, , vol. 46, # 16 p. 3546 - 3554
反应条件
1.1: 92 percent / triethylamine / dimethylformamide / 20 °C 2.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 2.2: tetrahydrofuran / 5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
1.1: 90 percent / toluene / 14 h / Heating 2.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 2.2: tetrahydrofuran / 5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
1.1: 92 percent / triethylamine / dimethylformamide / 20 °C 2.1: n-BuLi / tetrahydrofuran / 3 h / -78 °C 2.2: tetrahydrofuran / 5 h / 20 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 16, # 22 p. 5767 - 5772
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran T=20°C; 1 h;
参考文献
Lee, Ruey-min; Simoni, Daniele
Patent: US2008/261982 A1, 2008 ;
Location in patent: Page/Page column 9 ;
