反应条件
1: 1.) NaI, 2.) p-toluenesulfonic acid / 1.) acetone, reflux, 36 h, 2.) benzene, reflux, 24 h
2: 1.) hexamethyl phosphoric triamide, 2.) HCl / 1.) THF, hexane, -78 degC-RT 4 h, 2.) THF, water, 60 degC-70 degC, 1 h
4: 1.) O2, 2.) p-toluenesulfonic acid / 1.) Sensitox / 1.) CH2Cl2, 30 min, irradiation, 2.) benzene, 24 h, reflux
View Scheme
参考文献
Wasserman, Harry H.; Gambale, Ronald J.; Pulwer, Mitchell J.
Tetrahedron, 1981 , vol. 37, # 23 p. 4059 - 4067
