反应条件
1: 1) n-BuLi / 1) THF, 30 min, 2) 10 min
2: 78 percent / Pd(PPh3)4 / methanol; tetrahydrofuran / 30 h
4: 95 percent / 85percent formic acid
5: 72 percent / 1) LiBH4, 2) Pd(PPh3)4 / tetrahydrofuran / 1.5 h / Ambient temperature
6: 97 percent / KOH / methanol; H2O / 1 h / Ambient temperature
7: 1) 3-(5-nitro-2-oxo-1,2-dihydro-1-pyridyl)-1,2-benzisothiazole 1,1-dioxide, TEA, 2) TsOH / 1) 1,2-dichloroethane, 1.5 h, 2) 2 h, reflux
View Scheme
参考文献
Ahmed, Alauddin; Taniguchi, Nagahiro; Fukuda, Hirohiko; Kinoshita, Hideki; Inomata, Katsuhiko; Kotake, Hiroshi
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 3 p. 781 - 786
