5-苄氧基-4-甲氧基-2-硝基苯甲醛合成路线 （共 13 条）
反应条件
1: CF3COOH / 60 °C
2: 98 percent / 4-(dimethylamino)pyridine / 1 h
3: KF, 18-crown-8 / propan-2-ol / 5 h
4: acetic anhydride, sodium acetate / overnight
5: 94 percent / K2CO3 / ethanol / Ambient temperature
6: 43 percent / H2 / 10percent Pd/C / methanol / 2 h / 775.7 Torr
View Scheme
参考文献
Rogers, C. Bradford; Blum, Charles A.; Murphy, Bryan P.
Journal of Heterocyclic Chemistry, 1987 , vol. 24, p. 941 - 943
反应条件
ammonium hydroxide; sulfuric acid; potassium iodide; sodium nitrite; copper(l) iodide
1.) 5 min, 100 deg C 2.) AcOH, H2O; Yield given. Multistep reaction;
参考文献
Kobayashi, Shigeru; Okimoto, Kazuto; Imakura, Yasuhiro
Chemical & Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1567 - 1573
反应条件
sodium chlorite; aminosulfonic acid in water; tert-butyl alcohol
T=18°C; 2 h;
参考文献
Banwell, Martin G.; Hamel, Ernest; Ireland, Neil K.; Mackay, Maureen F.; Serelis, Algirdas K.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 16 p. 1905 - 1912
