2-氨基-5-(苄氧基)苯甲酸合成路线 （共 5 条）
反应条件
1: With sodium hydroxide; water in 1,4-dioxane
T=80°C; Heating / reflux;
2: With formic acid; water
pH=3 - 4;
3: Heating / reflux;
参考文献
Gruenenthal GmbH
Patent: US2008/293749 A1, 2008 ;
Location in patent: Page/Page column 15 ;
反应条件
sodium hydroxide in methanol
1 h; Heating;
参考文献
Borza, Istvan; Kolok, Sandor; Galgoczy, Kornel; Gere, Aniko; Horvath, Csilla; Farkas, Sandor; Greiner, Istvan; Domany, Gyoergy
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 2 p. 406 - 409
反应条件
1: SOCl2 / -20 - 20 °C
2: 50 °C
3: acetone / 4 h
4: HCl / methanol / 1 h / Heating
5: aq. NaOH / methanol / 1 h / Heating
View Scheme
参考文献
Borza, Istvan; Kolok, Sandor; Galgoczy, Kornel; Gere, Aniko; Horvath, Csilla; Farkas, Sandor; Greiner, Istvan; Domany, Gyoergy
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 2 p. 406 - 409
反应条件
1: 50 °C
2: acetone / 4 h
3: HCl / methanol / 1 h / Heating
4: aq. NaOH / methanol / 1 h / Heating
View Scheme
参考文献
Borza, Istvan; Kolok, Sandor; Galgoczy, Kornel; Gere, Aniko; Horvath, Csilla; Farkas, Sandor; Greiner, Istvan; Domany, Gyoergy
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 2 p. 406 - 409
反应条件
1: acetone / 4 h
2: HCl / methanol / 1 h / Heating
3: aq. NaOH / methanol / 1 h / Heating
View Scheme
参考文献
Borza, Istvan; Kolok, Sandor; Galgoczy, Kornel; Gere, Aniko; Horvath, Csilla; Farkas, Sandor; Greiner, Istvan; Domany, Gyoergy
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 2 p. 406 - 409
