反应条件
1: 1,3-dihydroxy-2-nitrobenzene With n-butyllithium in hexane; toluene
T=20°C; 0.25 h;
2: 1,4-dibromo-2-methyl-2-butene in hexane; toluene
T=110°C; 22 h;
参考文献
Kim, Mu-Yong; Na, Younghwa; Vankayalapati, Hariprasad; Gleason-Guzman, Mary; Hurley, Laurence H.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 14 p. 2958 - 2972
