3'-叠氮基-3'-脱氧腺苷合成路线 （共 3 条）
反应条件
1: 77 percent / TMSCl / pyridine 2: 100 percent / pyridine; H2O / 0.67 h / 20 °C 3: 95 percent / NH3; Ph3P / methanol; pyridine / 12 h / 20 °C 4: 62 percent / DCC; N-hydroxysuccinimide / dimethylformamide / 0 - 20 °C 5: 36 percent / TFA / 0.13 h / 20 °C View Scheme
参考文献
Robins, Morris J.; Miles, Robert W.; Samano, Mirna C.; Kaspar, Roger L.
Journal of Organic Chemistry, 2001 , vol. 66, # 24 p. 8204 - 8210
反应条件
1: 77 percent / TMSCl / pyridine 2: 100 percent / pyridine; H2O / 0.67 h / 20 °C 3: 95 percent / NH3; Ph3P / methanol; pyridine / 12 h / 20 °C View Scheme
参考文献
Robins, Morris J.; Miles, Robert W.; Samano, Mirna C.; Kaspar, Roger L.
Journal of Organic Chemistry, 2001 , vol. 66, # 24 p. 8204 - 8210
反应条件
hydrogen; palladium on activated charcoal in ethanol
P=760 Torr; 6 h;
参考文献
Botta, Oliver; Moyroud, Elisabeth; Lobato, Cinta; Strazewski, Peter
Tetrahedron, 1998 , vol. 54, # 44 p. 13529 - 13546
