2,4-二溴-6-甲基苯甲酸合成路线 （共 2 条）
反应条件
1: methyl-1,2,5-tribromobenzene With isopropylmagnesium chloride in tetrahydrofuran
T=-40°C; Grignard reaction; 2 h;
2: carbon dioxide in tetrahydrofuran
T=-40°C; 1 h; Further stages. Title compound not separated from byproducts.;
参考文献
Menzel, Karsten; Mills, Paul M.; Frantz, Doug E.; Nelson, Todd D.; Kress, Michael H.
Tetrahedron Letters, 2008 , vol. 49, # 3 p. 415 - 418
反应条件
1: hydrochloric acid / Diazotization.Behandlung der Diazoniumsalzloesung mit Kupferkaliumcyanuer
2: concentrated KOH-solution
View Scheme
参考文献
Claus; Beck
Justus Liebigs Annalen der Chemie, 1892 , vol. 269, p. 211
