2-乙基-3-甲基喹唑啉-4(3h)酮合成路线 （共 4 条）
反应条件
toluene-4-sulfonic acid
T=70°C; 3 h;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2004/111014 A1, 2004 ;
Location in patent: Page/Page column 263 ;
WO 2004/111014 A1
参考文献
Gotthelf
Journal of the American Chemical Society, 1901 , vol. 23, p. 617
反应条件
in formamide
T=170°C; 0.166667 h; Irradiation;
参考文献
Kostakis, Ioannis K.; Elomri, Abdelhakim; Seguin, Elisabeth; Iannelli, Mauro; Besson, Thierry
Tetrahedron Letters, 2007 , vol. 48, # 38 p. 6609 - 6613
反应条件
sodium hydride
1.) DMF, 5 min, 2.) 30 min; Yield given. Multistep reaction;
参考文献
Atkinson, Robert S.; Barker, Emma; Edwards, Paul J.; Thompson, Gordon
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1995 , # 12 p. 1533 - 1542
