4-甲氧基-4’-氰基联苯合成路线 （共 80 条）
反应条件
potassium fluoride; {palladium-dichloro-(P(C3H7)3)2} in N,N-dimethyl-formamide T=120°C;
参考文献
Gouda, Ken-Ichi; Hagiwara, Emiko; Hatanaka, Yasuo; Hiyama, Tamejiro
Journal of Organic Chemistry, 1996 , vol. 61, # 21 p. 7232 - 7233
反应条件
caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
反应条件
tetrabutylammomium bromide; caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
反应条件
in ethanol; n-heptane; dichloromethane; water; N,N-dimethyl-formamide
参考文献
Societe d'Expansion Scientifique Expansia
Patent: US6160157 A1, 2000 ;
反应条件
potassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane T=100 - 110°C; Suzuki coupling; Inert atmosphere;
参考文献
Chen, Guo-Jun; Han, Fu-She
European Journal of Organic Chemistry, 2012 , # 19 p. 3575 - 3579
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=20°C; 2 h;
参考文献
Amatore, Christian; Jutand, Anny; Negri, Serge; Fauvarque, Jean-Francois
Journal of Organometallic Chemistry, 1990 , vol. 390, # 3 p. 389 - 398
反应条件
1: 1-bromo-4-methoxy-benzene With magnesium in tetrahydrofuran 2: With zinc dibromide in tetrahydrofuran 3: para-bromobenzonitrile With 4-(N,N-dimethlyamino)pyridine; phosphonic acid diethyl ester; nickel dichloride in tetrahydrofuran T=50°C; Negishi cross-coupling; 48 h;
参考文献
Tetrahedron, , vol. 62, # 32 p. 7521 - 7533
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; ethylene glycol dimethyl ether in tetrahydrofuran T=20°C; 1 h;
参考文献
Journal of Organometallic Chemistry, , vol. 624, # 1-2 p. 376 - 379
反应条件
bis-triphenylphosphine-palladium(II) chloride; cesium fluoride in N,N-dimethyl-formamide T=80°C; Suzuki-Miyaura cross-coupling; 2 h; Inert atmosphere;
参考文献
PraveenGanesh, Nageswaran; Chavant, Pierre Yves
European Journal of Organic Chemistry, 2008 , # 27 p. 4690 - 4696
反应条件
anhydrous dipotassium phosphate; [1,3-bis(diphenylphosphino) propane] dichloronickel(II) in 1,4-dioxane T=100 - 110°C; Suzuki-Miyaura coupling reaction; Inert atmosphere;
参考文献
Gao, Han; Li, You; Zhou, Yi-Guo; Han, Fu-She; Lin, Ying-Jie
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 2-3 p. 309 - 314
