4-甲氧基-4’-氰基联苯合成路线 （共 80 条）
反应条件
in N,N-dimethyl-formamide 12 h; Reflux;
参考文献
Moorthy, Jarugu Narasimha; Koner, Apurba L.; Samanta, Subhas; Roy, Ankur; Nau, Werner M.
Chemistry - A European Journal, 2009 , vol. 15, # 17 p. 4289 - 4300
反应条件
tetrakis(triphenylphosphine) palladium(0) in tetrahydrofuran T=25°C; Negishi cross-coupling; 2 h; Inert atmosphere;
参考文献
Chemistry - A European Journal, , vol. 16, # 1 p. 248 - 253
反应条件
1: 70 percent / SnCl2, conc.HCl / propan-2-ol / 0.17 h / Heating 2: NaNO2, 10percent aq. H2SO4 / acetic acid / Heating 3: 57 percent / sodium isopropoxide / propan-2-ol / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 20, p. 1192 - 1195
Zhurnal Organicheskoi Khimii, , vol. 20, # 6 p. 1310 - 1314
反应条件
1: NaNO2, 10percent aq. H2SO4 / acetic acid / Heating 2: 57 percent / sodium isopropoxide / propan-2-ol / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 20, p. 1192 - 1195
Zhurnal Organicheskoi Khimii, , vol. 20, # 6 p. 1310 - 1314
反应条件
1: 20percent KOH / propan-2-ol / Heating 2: 57 percent / sodium isopropoxide / propan-2-ol / 1 h / Heating View Scheme
参考文献
Journal of Organic Chemistry USSR (English Translation), , vol. 20, p. 1192 - 1195
Zhurnal Organicheskoi Khimii, , vol. 20, # 6 p. 1310 - 1314
反应条件
1: PdCl2(dppf) / tetrahydrofuran / 0.25 h / 20 °C 2: 88 percent / PhPdI(PPh3)2 / dimethylformamide / 2 h / Heating View Scheme
参考文献
Russian Journal of Organic Chemistry, , vol. 31, # 11 p. 1480 - 1486
Zhurnal Organicheskoi Khimii, , vol. 31, # 11 p. 1650 - 1656
反应条件
1.1: sodium hydride / ethylene glycol dimethyl ether / 0.17 h / 0 - 20 °C / Inert atmosphere 1.2: 12 h / 0 - 20 °C / Inert atmosphere 2.1: potassium phosphate; bis(1,5-cyclooctadiene)nickel (0); tri-cyclo-hexyl-phosphine / tetrahydrofuran / 40 h / 25 °C / Inert atmosphere View Scheme
参考文献
Journal of Organic Chemistry, , vol. 76, # 24 p. 9946 - 9955
反应条件
HCN(CH2C(O)NHC6H5)CHCHN(CH2C6H5)(1+)*Cl(1-)=(HCN(CH2C(O)NHC6H5)CHCHN(CH2C6H5))Cl; potassium tert-butylate T=20 - 100°C; 24 h; Schlenk techniqueInert atmosphereGreen chemistry; Overall yield = 65 percentSpectr.; regioselective reaction;
参考文献
Advanced Synthesis and Catalysis, , vol. 356, # 2-3 p. 406 - 410
反应条件
1-methyl-pyrrolidin-2-one
参考文献
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), , p. 97 - 102
反应条件
ammonia; potassium carbonate; potassium bromide 1.) electrochemical reduction, -40 deg C, 2.) butanone, 70 deg C, 18 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Organic Chemistry, , vol. 53, # 7 p. 1496 - 1504
