4-溴-4′-甲氧基联苯合成路线 （共 57 条）
反应条件
boron trifluoride diethyl etherate; tris(dibenzylideneacetone)dipalladium (0) in ethylene glycol dimethyl ether; hexane T=20°C; 1 h;
参考文献
Saeki, Tomoyuki; Son, Eun-Cheol; Tamao, Kohei
Organic Letters, 2004 , vol. 6, # 4 p. 617 - 619
反应条件
bis-triphenylphosphine-palladium(II) chloride; sodium carbonate in tetrahydrofuran; water T=80°C; Suzuki-Miyaura cross-coupling;
参考文献
Kulhanek, Jiri; Bures, Filip; Ludwig, Miroslav
Beilstein Journal of Organic Chemistry, 2009 , vol. 5, art. no. 11
反应条件
tetrakis (triphenylphosphine) palladium (0) in ethylene glycol dimethyl ether; ethyl acetate
反应条件
palladium diacetate; potassium carbonate in methanol T=60°C; Suzuki Coupling; Inert atmosphere; chemoselective reaction;
参考文献
Liu, Jin-Biao; Yan, Hui; Chen, Hui-Xuan; Luo, Yu; Weng, Jiang; Lu, Gui
Chemical Communications, 2013 , vol. 49, # 46 p. 5268 - 5270
反应条件
1.1: BuLi / diethyl ether; hexane / 1 h / -78 °C 1.2: 63 percent / diethyl ether; hexane / 13 h / 20 °C 2.1: 60 percent / Ag2O / Pd(PPh3)4 / tetrahydrofuran / 36 h / 60 °C View Scheme
参考文献
Organic Letters, , vol. 1, # 2 p. 299 - 301
反应条件
copper(II) bis(trifluoromethanesulfonate) in 1,2-dichloro-ethane T=70°C; 72 h; regioselective reaction;
参考文献
Ciana, Claire-Lise; Phipps, Robert J.; Brandt, Jochen R.; Meyer, Falco-Magnus; Gaunt, Matthew J.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 2 p. 458 - 462
反应条件
1: With Argogel; tributylphosphine; azodicarboxylic acid bis[dimethylamide] in benzene Substitution; coupling to resin; 16 h; 2: With bromine in dichloromethane T=20°C; Bromination; degermylation; 0.666667 h; Further stages.;
参考文献
Spivey, Alan C.; Diaper, Christopher M.; Adams, Harry; Rudge, Andrew J.
Journal of Organic Chemistry, 2000 , vol. 65, # 17 p. 5253 - 5263
反应条件
boron trifluoride diethyl etherate; palladium diacetate in methanol T=20°C; 3 h;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 78, # 9 p. 1654 - 1658
反应条件
palladium 10 on activated carbon in methanol Suzuki-Miyaura cross-coupling; RefluxUnder air;
参考文献
Hanna Jr., James M.; Varnedoe, Lee S.; Angel, Brad D.; McClellan, Joshua L.
Letters in Organic Chemistry, 2010 , vol. 7, # 1 p. 1 - 6
反应条件
1: 84.6 percent / Na2CO3; Br2 / 1,2-dichloro-ethane / 50 °C 2: 83.8 percent / NaOH / H2O; ethanol / 6 h / Heating 3: sodium hydroxide / ethanol; H2O / Heating View Scheme
参考文献
Molecular Crystals and Liquid Crystals Science and Technology Section A: Molecular Crystals and Liquid Crystals, , vol. 339, p. 145 - 158
