2,2-二甲氧基-N-(噻吩-3-甲基)乙胺合成路线 （共 5 条）
反应条件
1: 91 percent / Et3N / ethyl acetate / 12 h / 15 - 20 °C 2: 49 percent / conc. HCl / dioxane / 16 h / Heating View Scheme
参考文献
Wikel, James H.; Denney, Michael L.; Vasileff, Robert T.
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 1 p. 289 - 290
反应条件
1: T=20°C; 60 h;
2: With hydrogen; palladium 10 on activated carbon in ethanol
P=2896.11 Torr;
参考文献
Nagarathnam, Dhanapalan; Khire, Uday; Asgari, Davoud; Shao, Jianxing; Liu, Xiao-Gao; Wang, Chunguang; Hart, Barry; Weber, Olaf; Lynch, Mark; Zhang, Lei; Wang, Lei
Patent: US2004/14755 A1, 2004 ;
Location in patent: Page/Page column 76 ;
US 20040014755 A1
反应条件
sodium tetrahydroborate in ethanol
2 h; Heating;
参考文献
McCarthy; Matthews; Broersma; McDermott; Kastner; Hornsperger; Demeter; Weintraub; Whitten
Journal of Medicinal Chemistry, 1990 , vol. 33, # 7 p. 1866 - 1873
反应条件
1: 16 h / 20 - 25 °C
2: H2 / 5percent Pd/C / ethanol / 12 h / 3102.9 Torr
View Scheme
参考文献
Wikel, James H.; Denney, Michael L.; Vasileff, Robert T.
Journal of Heterocyclic Chemistry, 1993 , vol. 30, # 1 p. 289 - 290
参考文献
Maffrand,J.P.; Eloy,F.
Journal of Heterocyclic Chemistry, 1976 , vol. 13, p. 1347 - 1349
