4-碘基-3-硝基苯甲醚合成路线 （共 16 条）
反应条件
1: With hydrogenchloride; sodium nitrite T=0°C; 2: With potassium iodide
参考文献
Wetzel, Alexander; Gagosz, Fabien
Angewandte Chemie - International Edition, 2011 , vol. 50, # 32 p. 7354 - 7358
反应条件
potassium iodide; sodium nitrite in hydrogenchloride; water
参考文献
Commissariat a l'Energie Atomique
Patent: US4795579 A1, 1989 ;
反应条件
pyridine; iodine; nitric acid T=160 - 170°C;
参考文献
Journal of the American Chemical Society, , vol. 52, p. 1570
反应条件
nitric acid; acetic acid
参考文献
Journal of Medicinal Chemistry, , vol. 53, # 2 p. 699 - 714
反应条件
T=160 - 170°C; auch in Gegenwart von Pyridin;
参考文献
Journal of the American Chemical Society, , vol. 52, p. 1570
反应条件
1: copper-powder; nitrobenzene 2: tin; aqueous HCl; acetic acid 3: aqueous KI / Diazotization.Erhitzen des Reaktionsprodukts mit Cu2O auf 350grad View Scheme
参考文献
Baker et al.
Journal of the Chemical Society, 1958 , p. 2658,2662
反应条件
1.1: phenyl-magnesium chloride / tetrahydrofuran / 0.42 h / -40 °C / Inert atmosphere 1.2: 4.5 h / -40 - 20 °C / Inert atmosphere 1.3: Inert atmosphere 2.1: trifluoroacetic acid / 16 h / 70 °C View Scheme
参考文献
Inman, Martyn; Carbone, Anna; Moody, Christopher J.
Journal of Organic Chemistry, 2012 , vol. 77, # 3 p. 1217 - 1232
反应条件
1: copper-powder / 130 - 170 °C 2: tin (II)-chloride; hydrogen chloride; acetic acid 3: NaNO2; aqueous HCl / Behandeln der Diazoniumsalz-Loesung mit wss. CuSO4 4: aqueous hydriodic acid View Scheme
参考文献
Hata; Tatematsu; Kubota
Bulletin of the Chemical Society of Japan, 1935 , vol. 10, p. 425
Chem. Zentralbl., 1936 , vol. 107, # I p. 546
反应条件
1: 80 percent / Cu powder / Pd(dba)2 / dimethylsulfoxide / 1 h / 50 °C 2: 97 percent / H2 / 10 percent Pd/C / methanol / 0.75 h / 735.51 Torr View Scheme
参考文献
Banwell, Martin G.; Kelly, Brian D.; Kokas, Okanya J.; Lupton, David W.
Organic Letters, 2003 , vol. 5, # 14 p. 2497 - 2500
反应条件
1: (i) NaOMe, Cu, (ii) NaOH, aq. EtOH 2: aq. NH3, <NH4>2Fe(SO4)2 3: 5 h / 200 °C / 1 Torr View Scheme
参考文献
Bennett,O.F. et al.
Journal of Heterocyclic Chemistry, 1975 , vol. 12, p. 1211 - 1213
